Garofalo, Smart to star in Wilmington medical drama

One Tree Hill won't be the only game in town in Wilmington for long. CBS' Untitled Medical Drama will start shooting at EUE/Screen Gems studios this month. The pilot is scheduled to shoot in the Port city for about three weeks. Then, it will be considered for pick up. New series are usually announced around the second week of May.

“This is great news for workers and the economy in the Southeastern part of the state,” said Governor Beverly Perdue. “This project will bring hundreds of jobs and much-needed revenue over the next few months and it is exactly what we expected once we were able to make North Carolina more competitive through an increased film tax credit.”

The ensemble drama from executive producer John Wells (“ER,” “Southland”) chronicles the travels of a mobile medical team that helps in medical crises around the country. The show's writer is Hannah Shakespeare (“Ghost Whisperer” and the 2007 “Bionic Woman” series).

“Twilight” actress Rachelle Lefevre is set to play the lead, a young and competent doctor. Actress Amy Smart also is attatched.

It was also announced that Janeane Garofalo is signed up. She will play "'Angel," the chief nurse and operations manager.